417716-92-8

Manufacturer supply top purity Lenvatinib 417716-92-8 with ISO standards We supply high quality Lenvatinib (CAS 417716-92-8), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Lenvatinib ?

Lenvatinib is , while it's Molecular Formula is C21H19ClN4O4. Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.

What is the CAS number for Lenvatinib ?

The CAS number of Lenvatinib is 417716-92-8.

More information of Lenvatinib 417716-92-8 are:

What is Lenvatinib (417716-92-8) used for?

Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRα, PDGFRβ and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces tumor growth in an H146 small cell lung cancer mouse xenograft model and induces tumor regression when administered at a dose of 100 mg/kg twice per day. Formulations containing lenvatinib have been used in the treatment of differentiated thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

InChI:InChI=1/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)

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How to get the best price on Lenvatinib?

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