
67-73-2
- Product Name:Fluocinone Acetate
- Molecular Formula:C24H30F2O6
- Purity:99%
- Molecular Weight:452.495
Product Details;
CasNo: 67-73-2
Molecular Formula: C24H30F2O6
Appearance: Crystalline Solid
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What is the Fluocinolone acetonide ?
Fluocinolone acetonide is Crystalline Solid, while it's Molecular Formula is C24H30F2O6. Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.
What is the CAS number for Fluocinolone acetonide ?
The CAS number of Fluocinolone acetonide is 67-73-2.
More information of Fluocinolone acetonide 67-73-2 are:
Synonyms |
Pregna-1,4-diene-3,20-dione,6a,9-difluoro-11b,16a,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone(6CI,8CI);16a,17a-Isopropylidene-6a,9a-difluoro-1,4-pregnadiene-11b,16a,17a,21-tetrol-3,20-dione;6a,9-Difluoro-11b,21-dihydroxy-16a,17a-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione;6a,9a-Difluoro-16a,17a-isopropylidenedioxy-D1-hydrocortisone;6a,9a-Difluoro-16a-hydroxyprednisolone16,17-acetonide;6a-Fluorotriamcinolone acetonide;Coriphate;Cortiplastol;Dermalar;Dermatin;Dermatin (steroid);Fluocinolone 16,17-acetonide;Fluovitef;Fluvean;Jellin;Localyn;NSC 92339;Percutina;Sinaflan;Sinalar;Synaflan;Synamol;Synandrone;Synemol;Synsac;Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-; |
CAS Number |
67-73-2 |
Molecular Formula |
C24H30F2O6 |
Molecular Weight |
452.495 |
Density |
1.36 g/cm3 |
Melting Point |
267-269 °C(lit.) |
Boiling Point |
578.5 °C at 760 mmHg |
Flash Point |
303.7 °C |
HS CODE |
2937220000 |
PSA |
93.06000 |
LogP |
2.36680 |
Pka |
12.78±0.70(Predicted) |
What is Fluocinolone acetonide (67-73-2) used for?
Fluocinolone acetonide is a synthetic fluorinated corticosteroid and a synthetic glucocorticoid VEGF inhibitor, known for its anti-inflammatory properties. It is primarily used in dermatology to reduce skin inflammation and relieve itching. It also acts as an inhibitor of tumor cells and can regulate lipid metabolism by modulating gene expression. Due to its high glucocorticoid receptor affinity, it can inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line and inhibit TNF-α angiogenesis.
Used in Dermatology:
Fluocinolone acetonide is used as an anti-inflammatory agent for the treatment of various skin conditions, including eczema, neurodermatitis, skin pruritus, contact dermatitis, psoriasis, and dermatitis. It helps reduce skin inflammation and relieve itching, providing relief to patients suffering from these conditions.
Used in Oncology:
Fluocinolone acetonide is used as a tumor cell inhibitor, potentially offering therapeutic benefits in cancer treatment. Its ability to regulate lipid metabolism and modulate gene expression may contribute to its anti-tumor effects.
Used in Ophthalmology:
Fluocinolone acetonide is used to inhibit the expression of VEGF in the retinal pigment epithelial cell line, making it a potential treatment option for conditions related to ocular angiogenesis, such as age-related macular degeneration or diabetic retinopathy.
Used in Anti-inflammatory Applications:
As a synthetic glucocorticoid VEGF inhibitor, fluocinolone acetonide is used for its anti-inflammatory properties, which can be beneficial in managing inflammation in various medical conditions.
InChI:InChI=1/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13?,14?,16-,17-,19+,21-,22-,23-,24+/m0/s1
Articles related to Fluocinolone acetonide:
Article |
Source |
Method for preparing high-purity fluocinolone acetonide |
- Paragraph 0016-0027, (2020/02/18) |
Improved synthesis of fluocinolone acetonide and process research of 6α,9α-fluorination |
Tang, Jie,Zeng, Chunling,Xie, Longyong,Wang, Jinghua,Tian, Mi,Guo, Cancheng supporting information, p. 110 - 112 (2018/01/26) |
How to get the best price on Fluocinolone acetonide?
Shandong Hanjiang Chemical Co., Ltd. is a quality supplier and manufacturer of Fluocinolone acetonide . You can buy high quality, low price Fluocinolone acetonide 67-73-2 here. Contact us.
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