67-73-2

  • Product Name:Fluocinone Acetate
  • Molecular Formula:C24H30F2O6
  • Purity:99%
  • Molecular Weight:452.495
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Product Details;

CasNo: 67-73-2

Molecular Formula: C24H30F2O6

Appearance: Crystalline Solid

Factory Sells Best Quality Fluocinone Acetate 67-73-2 with steady supply We supply high quality Fluocinolone acetonide (CAS 67-73-2), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Fluocinolone acetonide ?

Fluocinolone acetonide is Crystalline Solid, while it's Molecular Formula is C24H30F2O6. Fluocinolone acetonide is primarily used in dermatology to reduce skin inflammation and relieve itching. It acts as an inhibitor of tumor cells and it can regulate lipid metabolism by modulating gene expression. It can also inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, it can inhibit TNF-α angiogenesis.

What is the CAS number for Fluocinolone acetonide ?

The CAS number of Fluocinolone acetonide is 67-73-2.

More information of Fluocinolone acetonide 67-73-2 are:

Synonyms

Pregna-1,4-diene-3,20-dione,6a,9-difluoro-11b,16a,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone(6CI,8CI);16a,17a-Isopropylidene-6a,9a-difluoro-1,4-pregnadiene-11b,16a,17a,21-tetrol-3,20-dione;6a,9-Difluoro-11b,21-dihydroxy-16a,17a-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione;6a,9a-Difluoro-16a,17a-isopropylidenedioxy-D1-hydrocortisone;6a,9a-Difluoro-16a-hydroxyprednisolone16,17-acetonide;6a-Fluorotriamcinolone acetonide;Coriphate;Cortiplastol;Dermalar;Dermatin;Dermatin (steroid);Fluocinolone 16,17-acetonide;Fluovitef;Fluvean;Jellin;Localyn;NSC 92339;Percutina;Sinaflan;Sinalar;Synaflan;Synamol;Synandrone;Synemol;Synsac;Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,11b,16a)-;

CAS Number

67-73-2

Molecular Formula

C24H30F2O6

Molecular Weight

452.495

Density

1.36 g/cm3

Melting Point

267-269 °C(lit.)

Boiling Point

578.5 °C at 760 mmHg

Flash Point

303.7 °C

HS CODE

2937220000

PSA

93.06000

LogP

2.36680

Pka

12.78±0.70(Predicted)

What is Fluocinolone acetonide (67-73-2) used for?

Fluocinolone acetonide is a synthetic fluorinated corticosteroid and a synthetic glucocorticoid VEGF inhibitor, known for its anti-inflammatory properties. It is primarily used in dermatology to reduce skin inflammation and relieve itching. It also acts as an inhibitor of tumor cells and can regulate lipid metabolism by modulating gene expression. Due to its high glucocorticoid receptor affinity, it can inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line and inhibit TNF-α angiogenesis.
Used in Dermatology:
Fluocinolone acetonide is used as an anti-inflammatory agent for the treatment of various skin conditions, including eczema, neurodermatitis, skin pruritus, contact dermatitis, psoriasis, and dermatitis. It helps reduce skin inflammation and relieve itching, providing relief to patients suffering from these conditions.
Used in Oncology:
Fluocinolone acetonide is used as a tumor cell inhibitor, potentially offering therapeutic benefits in cancer treatment. Its ability to regulate lipid metabolism and modulate gene expression may contribute to its anti-tumor effects.
Used in Ophthalmology:
Fluocinolone acetonide is used to inhibit the expression of VEGF in the retinal pigment epithelial cell line, making it a potential treatment option for conditions related to ocular angiogenesis, such as age-related macular degeneration or diabetic retinopathy.
Used in Anti-inflammatory Applications:
As a synthetic glucocorticoid VEGF inhibitor, fluocinolone acetonide is used for its anti-inflammatory properties, which can be beneficial in managing inflammation in various medical conditions.

InChI:InChI=1/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13?,14?,16-,17-,19+,21-,22-,23-,24+/m0/s1

Articles related to Fluocinolone acetonide:

Article

Source

Method for preparing high-purity fluocinolone acetonide

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Paragraph 0016-0027, (2020/02/18)

Improved synthesis of fluocinolone acetonide and process research of 6α,9α-fluorination

Tang, Jie,Zeng, Chunling,Xie, Longyong,Wang, Jinghua,Tian, Mi,Guo, Cancheng

supporting information, p. 110 - 112 (2018/01/26)

How to get the best price on Fluocinolone acetonide?

Shandong Hanjiang Chemical Co., Ltd. is a quality supplier and manufacturer of Fluocinolone acetonide . You can buy high quality, low price Fluocinolone acetonide 67-73-2 here. Contact us.

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