82034-46-6
- Product Name：Loteprednol etabonate
- Molecular Formula：C24H31ClO7
- Purity：99%
- Molecular Weight：466.959
Product Details;
CasNo： 82034-46-6
Molecular Formula： C24H31ClO7
Quality products make an important contribution to long-term revenue and profitability. Reputable supplier selling Loteprednol etabonate 82034-46-6 with stock
1.What is the Loteprednol etabonate ?
An ophthalmic corticosteroid. Used as an anti-inflammatory.
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593-71-5
Chloroiodomethane
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![17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic ethoxycarboxylic anhydride](/upload/2025/4\1f0f9cfe-fa66-4cf5-a295-d3fcc4a0b6ca.png)
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133991-62-5
17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic ethoxycarboxylic anhydride
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82034-46-6
Loteprednol etabonate
| Conditions | Yield |
|---|---|
|
17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic ethoxycarboxylic anhydride;
With
sodium ethanolate;
In
N,N,N,N,N,N-hexamethylphosphoric triamide;
at 20 ℃;
for 24h;
Large scale;
Chloroiodomethane;
In
N,N,N,N,N,N-hexamethylphosphoric triamide;
at 20 ℃;
for 2h;
Large scale;
|
89% |
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-
49715-04-0
chlorosulfuric acid chloromethyl ester
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17α-ethoxycarbonyloxy-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic acid
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82034-46-6
Loteprednol etabonate
| Conditions | Yield |
|---|---|
|
With
tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate;
In
dichloromethane;
at 20 ℃;
for 2h;
Time;
|
92.8% |
2.What is the CAS number for Loteprednol etabonate ?
The CAS number of Loteprednol etabonate is 82034-46-6.
More information of Loteprednol etabonate 82034-46-6 are:
|
CAS Number |
82034-46-6 |
|
Density |
1.31 g/cm3 |
|
Melting Point |
220.5-223.5 °C |
|
Boiling Point |
600.1 °C at 760 mmHg |
|
Flash Point |
316.7 °C |
|
Vapor Pressure |
6.65E-17mmHg at 25°C |
|
Refractive Index |
1.57 |
|
HS CODE |
2937229000 |
|
PSA |
99.13000 |
|
LogP |
3.91650 |
|
Pka |
14.06±0.70(Predicted) |
3.What are another words for Loteprednol etabonate ?
Synonyms for Loteprednol etabonate 82034-46-6:Alrex;CDDD 5604;HGP 1;Lotemax;
4.What is the molecular formula of Loteprednol etabonate?
The chemical formula of Loteprednol etabonate is C24H31ClO7 which containing 24 Carbon atoms,31 Hydrogen atoms,1 Chlorine atoms and 7 Oxygen atoms,and the molecular weight of Loteprednol etabonate is 466.959.
5.What is Loteprednol etabonate (82034-46-6) used for?
Loteprednol etabonate was introduced in the US as Lotemax (opththalmic suspension at 0.5%) for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the ocular globe, and as Alrex (opththalmic suspension at 0.2%) for the symptomatic treatment of seasonal allergic conjunctivitis. Loteprednol etabonate is a novel soft corticosteroid with a superior efficacy and an improved safety profile compared to prior ophthalmic steroids due to its metabolic lability and a fast enzymatic transformation to inactive metabolite. A combination of Lotemax with the antibiotic Tobramycin is currently under development.
InChI:InChI=1/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1
Relevant articles related to Loteprednol etabonate:
|
Article |
Source |
|
A method for synthesizing loteprednol etabonate and a method for synthesizing intermediate (by machine translation) |
- Paragraph 0025; 0031; 0032, (2017/05/05) |
|
Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
- , (2008/06/13) |
6.Buy Loteprednol etabonate with the best price .
Shandong Hanjiang Chemical Co., Ltd. is a quality supplier of Loteprednol etabonate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Loteprednol etabonate 82034-46-6.
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