2894-61-3
- Product Name：7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one
- Molecular Formula：C15H11 Br N2 O
- Purity：99%
- Molecular Weight：315.169
Product Details;
CasNo： 2894-61-3
Molecular Formula： C15H11 Br N2 O
Quality products make an important contribution to long-term revenue and profitability. We supply reliable quality 2894-61-3 in stock, fast delivery.
1.What is the 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one ?
7-Bromo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one inhibits HIV-1 reverse transcription.
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- 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
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![7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one](/upload/2023/5\c30731d9-be1a-4c99-9e76-528c6d1fb598.png)
- 2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
| Conditions | Yield |
|---|---|
|
With sulfuric acid; bromine; In acetic acid; at 20 ℃; for 48h;
|
90% |
|
With sulfuric acid; bromine; In acetic acid;
|
65.9% |
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- 56-40-6,18875-39-3,25718-94-9
glycine
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- 34099-70-2
7-bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
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- 612527-22-7
C17H14BrN3O2
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- 2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
| Conditions | Yield |
|---|---|
|
With water; sodium carbonate; In ethanol; for 5h; Heating / reflux;
|
67% |
2.What is the CAS number for Desalkylgidazepam?
The CAS number of Desalkylgidazepam is 2894-61-3.
More information of Desalkylgidazepam 2894-61-3 are:
|
CAS Number |
2894-61-3 |
|
Density |
1.51g/cm3 |
|
Melting Point |
220-221 °C(Solv: ethyl ether (60-29-7)) |
|
Boiling Point |
464.8°Cat760mmHg |
|
Flash Point |
234.9°C |
|
Vapor Pressure |
8.13E-09mmHg at 25°C |
|
Refractive Index |
1.68 |
|
HS CODE |
2933990090 |
|
PSA |
44.95000 |
|
LogP |
2.75930 |
|
Pka |
11.72±0.70(Predicted) |
3.What are another words for 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one ?
Synonyms for 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one 2894-61-3:7-Bromo-5-phenyl-1,3-dihydrobenzo[e]-1,4-diazepin-2-one;7-Bromo-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one;7-Bromo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; BD 3; BD 3(tranquilizer); Desalkylgidazepam
4.What is the molecular formula of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one?
The chemical formula of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one is C15H11 Br N2 O which containing 15 Carbon atoms,1 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one is 315.169.
5.What is 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one (2894-61-3) used for?
Bromonordiazepam is the active metabolite of of the Soviet developed Gidazepam. Bromonordiazepam is closely related is to Diazepam in structure, has a very long half life and is exceptionally anxiolytic with limited non-therapeutic potential. It was assumed that desalkylgidazepam as gidazepam in rabbits and monkeys might contribute to the formation of pharmacological effects, in rats and man its pharmacological action was realized entirely by virtue of desalkylgidazepam.
InChI:InChI=1/C15H11BrN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
Relevant articles related to 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one:
|
Article |
Source |
| Designer Benzodiazepines Gidazepam and Desalkygidazepam (Bromonordiazepam): What Do We Know? | Journal of Analytical Toxicology, Volume 47, Issue 4, May 2023, Pages 324–331, |
| The blood-to-plasma ratio and predicted GABAA-binding affinity of designer benzodiazepines |
In this work, the same QSAR model was applied to nine designer benzodiazepines reported to the EMCDDA, plus gidazepam and its metabolite, desalkylgidazepam , Forensic Toxicology volume 40, pages349–356 (2022) |
6.Reliable quality 2894-61-3 in stock, fast delivery.
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