2886-65-9
- Product Name：7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Molecular Formula：C15H10ClFN2O
- Purity：99%
- Molecular Weight：288.709
Product Details;
CasNo： 2886-65-9
Molecular Formula： C15H10ClFN2O
Appearance： Light yellow solid
Quality products make an important contribution to long-term revenue and profitability. High purity 2886-65-9 good supplier with reliable price.
1.What is the 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ?
7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is the major human metabolite of flurazepam. This is a controlled drug precursor therefore a liscence may be required for purchase. The major metabolite, N-desalkylflurazepam, shows a plasma concentration in man after flurazepam administration that is at least 50 times as high as the flurazepam concentration. Desalkylflurazepam, also known as N-desalkyl-2-oxoquazepam, is a long-acting metabolite of the benzodiazepine drug flurazepam.
-
- 1584-62-9
2?(2?bromoacetamido)?5?chloro?2'?fluorobenzophenone
-
- 2886-65-9
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one
| Conditions | Yield |
|---|---|
|
With ammonia; In methanol; at 0 ℃; Reflux;
|
70% |
|
With ammonium hydroxide; In methanol; diethyl ether; at 20 ℃; for 46h;
|
|
|
With ammonia; In methanol; at 45 ℃;
|
18.65 g |
-
- 2836-40-0
2-(2-chloroacetyl)amino-4-chloro-2'-fluorobenzophenone
-
- 2886-65-9
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one
| Conditions | Yield |
|---|---|
|
With paraformaldehyde; In methanol; ammonia; water;
|
71% |
|
With hexamethylenetetramine; ammonium chloride; In ethanol; for 4h; Heating;
|
|
|
With ammonium acetate; hexamethylenetetramine; In ethanol; Reflux;
|
2.What is the CAS number for 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ?
The CAS number of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is 2886-65-9.
More information of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 2886-65-9 are:
|
CAS Number |
2886-65-9 |
|
Density |
1.39 g/cm3 |
|
Melting Point |
204-206 °C |
|
Boiling Point |
454 °C at 760 mmHg |
|
Flash Point |
228.4 °C |
|
Vapor Pressure |
1.97E-08mmHg at 25°C |
|
Refractive Index |
1.647 |
|
HS CODE |
2933997500 |
|
PSA |
41.46000 |
|
LogP |
2.84220 |
|
Pka |
11.55±0.70(Predicted) |
3.What are another words for 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ?
Synonyms for 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 2886-65-9:2H-1,4-Benzodiazepin-2-one,7-chloro-5-(o-fluorophenyl)-1,3-dihydro- (7CI,8CI);7-Chloro-1,3-dihydro-5-(2'-fluorophenyl)-2H-1,4-benzodiazapin-2-one;7-Chloro-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one;7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one;7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one;CM 7116;Descarbethoxyloflazepate;N-1-Desalkylflurazepam;N-Desalkyl-2-oxoquazepam;N-Desalkylflutoprazepam;Norfludiazepam;Norflurazepam;Norflutoprazepam;Ro 5-3367;Sch 17514;
4.What is the molecular formula of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one?
The chemical formula of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is C15H10ClFN2O which containing 15 Carbon atoms,10 Hydrogen atoms,1 Chlorine atoms,1 Fluorine atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is 288.709.
5.What is N-desalkylflurazepam (2886-65-9) used for?
N‐desalkylflurazepam (NF) is an analytical reference material that is structurally categorized as a benzodiazepine. N-desalkylflurazepam reduced the amplitudes of the occipital visual evoked potentials (VEPs) to sine-wave gratings to a greater extent than the amplitudes of the late parietal EPs to amoeboid shapes.
C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F
InChI:InChI=1/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
Relevant articles related to 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one:
|
Article |
Source |
|
One-pot microwave-assisted synthesis and antimalarial activity of ferrocenyl benzodiazepines |
Mwande-Maguene, Gabin,Jakhlal, Jouda,Lekana-Douki, Jean-Bernard,Mouray, Elisabeth,Bousquet, Till,Pellegrini, Sylvain,Grellier, Philippe,Ndouo, Fousseyni Samba Toure,Lebibi, Jacques,Pelinski, Lydie , p. 2412 - 2415 (2012/01/04) |
| Prevalence and concentrations of sedative-hypnotic drugs in blood of drivers involved in road traffic crashes in the Padova region of Italy–not so easy to interpret |
…diazepam had the highest percentage of cases (92–100%) with concentrations below the lower limit of the therapeutic range, while clonazepam, triazolam, and N-desalkylflurazepam … , Forensic science international, 2022 |
6.High purity 2886-65-9 good supplier with reliable price.
Shandong Hanjiang Chemical Co., Ltd. is a quality supplier of 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one. Our main goal is customer satisfaction. Contact us to negotiate the reliable price for your business on N-desalkylflurazepam 2886-65-9.
Relevant Products
-
2-Chloromethyl-5-trifluoromethyl-[1,3,4]oxadiazoleCAS：723286-98-4
-
Helional,2-Methyl-3-(3,4-methylenedioxyphenyl)propanalCAS：1205-17-0
-
Nandrolone decanoateCAS：360-70-3
