1485-00-3

  • Product Name:3,4-Methylenedioxy-beta-nitrostyrene
  • Molecular Formula:C9H7NO4
  • Purity:99%
  • Molecular Weight:193.159
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Product Details;

CasNo: 1485-00-3

Molecular Formula: C9H7NO4

Appearance: yellow powder

Quality products make an important contribution to long-term revenue and profitability. Best quality 1485-00-3 good producer with reliable price.

1.What is the 3,4-Methylenedioxy-beta-nitrostyrene ?

MNS (3,4-Methylenedioxy-β-nitrostyrene) is equally potent as inhibitors of platelet aggregation as 3,4-dimethoxy-β-nitrostyrene. MDBN is a Src and Syk kinase inhibitor that prevents phosphorylation and cytoskeletal association of GPIIb/IIIa and talin. Inflammasome inhibitors NLRP3-IN-2, JC124, and 3,4-methylenedioxy-β-nitrostyrene (MNS) were previously reported to exert anti-inflammatory effects in various disease models but not in the dextran sulfate sodium (DSS)–induced colitis model.

piperonal
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piperonal

nitromethane
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nitromethane

5-(2-nitrovinyl)benzo[1,3]dioxole
1485-00-3

5-(2-nitrovinyl)benzo[1,3]dioxole

Conditions
Conditions Yield
With sodium acetate; methylamine; In methanol; ethanol; for 2h;
91%
With aluminum oxide; potassium carbonate; for 0.0666667h; microwave irradiation;
90%
With ethylenediamine functionalized magnetic Fe3O4 supported on SiO2 nanoparticles; air; at 80 ℃; for 4h;
89%
With ammonium acetate; In acetic acid; for 1.75h; Heating;
87%
With ammonium acetate; In acetic acid; for 2h; Reflux;
70%
With ammonium acetate; In acetic acid; at 2 ℃; for 50h;
52%
With ethanol; methylamine hydrochloride; sodium carbonate;
 
With methanol; potassium hydroxide; ethanol; Man giesst das Reaktionsgemisch in eisgekuehlte verduennte Salzsaeure;
 
 
 
With ammonium acetate; acetic acid; for 1.5h; Heating;
 
With ammonium acetate; Heating;
 
With ammonium acetate; acetic acid;
 
With methylamine; In methanol; for 4h;
 
With sodium hydroxide; In methanol; water; at 0 - 5 ℃; for 1h;
 
With cyclohexylamine; acetic acid; for 6h; Reflux;
 
With ammonium acetate; In acetic acid; at 20 ℃; for 1.5h; Reflux;
 
With ammonium acetate; acetic acid; for 1.5h; Reflux;
 
With ammonium acetate; acetic acid; for 1.5h; Reflux;
 
With ammonium acetate; acetic acid; at 90 ℃; for 4h;
 
With ammonium acetate; acetic acid; at 100 ℃;
 
Alkaline conditions;
 
With sodium hydroxide; In methanol; water; at 15 ℃; Inert atmosphere;
 
With ethylenediamine; at 20 ℃; for 120h; Darkness;
 
With acetic acid; N-butylamine; for 4h; Reflux;
 
With sodium hydroxide; In methanol; at 0 - 20 ℃; for 2h; Inert atmosphere;
 
With ammonium acetate; In acetic acid; Sonication;
 
With ammonium acetate; In acetic acid; for 1 - 2h; Reflux;
 
With ammonium acetate; acetic acid; for 2h; Reflux;
 
With ethanolamine supported on silica gel; at 90 ℃; for 6h;
 
With ammonium acetate; acetic acid; at 100 ℃; for 3h;
 
With methylamine; In methanol; at 50 ℃; for 3.5h;
 
With sodium hydroxide; In methanol; at 0 - 20 ℃; for 2h; Temperature; Reagent/catalyst;
 
With sodium hydroxide; In methanol; at 0 ℃;
 
1,3-benzodioxol-5-ylmethyl amine
2620-50-0

1,3-benzodioxol-5-ylmethyl amine

nitromethane
75-52-5

nitromethane

5-(2-nitrovinyl)benzo[1,3]dioxole
1485-00-3

5-(2-nitrovinyl)benzo[1,3]dioxole

Conditions
Conditions Yield
With 4-(4-fluorophenyl)naphthalene-1,2-dione; oxygen; at 80 ℃; for 12h;
53%

2.What is the CAS number for 3,4-Methylenedioxy-beta-nitrostyrene ?

The CAS number of 3,4-Methylenedioxy-beta-nitrostyrene is 1485-00-3.

More information of 3,4-Methylenedioxy-beta-nitrostyrene 1485-00-3 are:

CAS Number

1485-00-3

Density

1.401 g/cm3

Melting Point

159-163 °C

Boiling Point

334.862 °C at 760 mmHg

Flash Point

168.837 °C

Vapor Pressure

0.000242mmHg at 25°C

Refractive Index

1.5200 (estimate)

HS CODE

29329990

PSA

64.28000

LogP

2.18590

3.What are another words for 3,4-Methylenedioxy-beta-nitrostyrene ?

Synonyms for 3,4-Methylenedioxy-beta-nitrostyrene 1485-00-3:Styrene,3,4-(methylenedioxy)-b-nitro- (6CI,7CI,8CI);1-(2-Nitrovinyl)-3,4-methylenedioxybenzene;3,4-(Methylenedioxy)-b-nitrostyrene;3,4-Methylenedioxy-1-(2-nitrovinyl)benzene;5-(2-Nitrovinyl)-1,3-benzodioxole;5-(2-Nitrovinyl)benzodioxole;NSC 10120;NSC105303;NSC 170724;

4.What is the molecular formula of 3,4-Methylenedioxy-beta-nitrostyrene?

The chemical formula of  3,4-Methylenedioxy-beta-nitrostyrene is C9H7NO4 which containing 9 Carbon atoms,7 Hydrogen atoms,1 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of  3,4-Methylenedioxy-beta-nitrostyrene is 193.159.

5.What is 3,4-Methylenedioxy-beta-nitrostyrene (1485-00-3) used for?

MDBN (1485-00-3) is an irreversible inhibitor of p97 (IC50 < 10 μM). Cell permeable. In some studies, 3,4-Methylenedioxy-beta nitrostyrene (MNS) was demonstrated to decrease GTP binding and inhibit GTPase activity (IC50=23.92μM) while the compound N-phenylanthranilic acid increased GTP binding (EC50=4.969μM) and decreased GTPase activity.

InChI:InChI=1/C9H7NO4/c11-10(12)4-3-7-1-2-8-9(5-7)14-6-13-8/h1-5H,6H2/b4-3-

Relevant articles related to 3,4-Methylenedioxy-beta-nitrostyrene:

Article

Source

3,4-methylenedioxy-beta-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome

Y. He et al.

, J. Biol. Chem. (2014)

3,4-Methylenedioxy-beta-nitrostyrene ameliorates experimental burn wound progression by inhibiting the NLRP3 inflammasome activation.

Xiao M, Li L, Li C, Liu L, Yu Y, Ma L.

, Plast Reconstr Surg. (2016) 137:566e−75e.

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Shandong Hanjiang Chemical Co., Ltd. is a quality supplier of 3,4-Methylenedioxy-beta-nitrostyrene. Our main goal is customer satisfaction. Contact us to negotiate the reliable price for your business on 3,4-Methylenedioxy-beta-nitrostyrene 1485-00-3, good producer.

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